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Role Snapshot

Handshake is seeking Chemistry PhDs for flexible, hourly contract work to evaluate AI-generated content and provide feedback on chemical reasoning, experimental design, and scientific accuracy. This project-based opportunity supports AI research while allowing participants to maintain their primary academic or professional roles.

Key Responsibilities: Design rigorous, domain-relevant chemistry questions and review AI-generated responses for scientific accuracy, logical consistency, and chemical validity. Evaluate AI understanding of reaction mechanisms, experimental design, data interpretation, and technical problem-solving in chemistry.
Skills & Tools: Advanced chemical reasoning across multiple subdisciplines (organic, inorganic, physical, analytical, materials, or computational chemistry) with expertise in experimental design, reaction mechanisms, and data analysis. Strong scientific writing and critical evaluation skills; prior AI experience is not required.
Qualifications: PhD or doctoral student in Chemistry or closely related fields with strong background in advanced chemical reasoning and core chemistry principles. Work authorization in the USA (including eligible F-1 CPT/OPT or other supported visa categories).
Location: Remote - Remote (USA)
Compensation: $120Kโ€“$180K/yr (estimated)

Job Description

Overview

Handshake is seeking Chemistry PhDs to support AI research through flexible, hourly contract work. This is not a traditional academic or full-time role. Youโ€™ll use your advanced chemistry training to evaluate AI-generated content and provide feedback that helps AI better understand chemical reasoning, experimental design, reaction mechanisms, data interpretation, and technical problem-solving.

This is an ongoing, project-based opportunity that can be done alongside research, teaching, postdoctoral work, or industry employment.


About Handshake AI

Details

  • This project involves using your experience in chemistry to design rigorous, domain-relevant questions and review AI-generated responses for scientific accuracy, logical consistency, and chemical validity. No prior AI or technical experience is required.

  • Fully remote with a flexible, asynchronous schedule and no minimum hour requirement; most contributors work approximately 5โ€“20 hours per week when participating in an active project.

  • Placement depends on current project needs, with opportunities to be considered for future projects as they become available.

Qualifications

  • Doctoral students and graduates (including those currently enrolled in a PhD program or in postdoctoral positions) in Chemistry or closely related fields.

  • Strong background in advanced chemical reasoning, experimental design, reaction mechanisms, data analysis, and core principles across subdisciplines such as organic, inorganic, physical, analytical, materials, or computational chemistry.

Work authorization information

F-1 students who are eligible for CPT or OPT may be eligible for projects on Handshake AI. Work with your Designated School Official to determine your eligibility. If your school requires a CPT course, Handshake AI may not meet your schoolโ€™s requirements. STEM OPT is not supported. See our Help Center article for more information on what types of work authorizations are supported on Handshake AI.

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